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Histological Study of the Effect of Bioactive Glass on Tibial Bone Repair in Rats
Gamal Abdel Salam,
Ali M. Ali,
Osama F. Ahmed,
Ibrahim S. Ali
Issue:
Volume 1, Issue 2, July 2015
Pages:
13-21
Received:
26 May 2015
Accepted:
3 June 2015
Published:
11 June 2015
Abstract: The main goal of this study was to histologically evaluate the healing of surgically created defects on the tibiae of adult rats after implantation of bioactive glass. Twenty adult Wistar rats (body weight of 300g) were divided into two groups: bioglass treated group (n=10) and control group (n=10). Unicortical bone defects with 3-mm diameter were performed in both tibiae of the animals and filled with bioglass particles. The rats were then sacrificed at 14, 30 , 60 and 90 days, and the tissues were prepared for histological processing, sectioning, and staining with hematoxylin and eosin, as well as Mallory trichrome, and analyzed under light microscope. Within 7-14 days, both groups presented connective tissue septa with new bone formation, more intense in bioglass treated group. In the subsequent periods (30, 60 and 90 days), these groups presented more mature bone tissue around the glass particles. Bone trabeculae formed in all experimental periods were juxtaposed to the glass particles. It can be concluded that bioglass materials promoted bone formation over the entire extension of the defect, independently of the size of the granules, thus confirming their biological osteoconductive property.
Abstract: The main goal of this study was to histologically evaluate the healing of surgically created defects on the tibiae of adult rats after implantation of bioactive glass. Twenty adult Wistar rats (body weight of 300g) were divided into two groups: bioglass treated group (n=10) and control group (n=10). Unicortical bone defects with 3-mm diameter were ...
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Age-related Measurements and Indices of Normal Human Brain Fourth Ventricle: A Computed Tomography Study
Abd El-Wanees A. Al-Awdan,
Saadia A. Shalaby,
Essam M. Mehlab,
Amal M. El Shazly
Issue:
Volume 1, Issue 2, July 2015
Pages:
22-31
Received:
1 June 2015
Accepted:
12 June 2015
Published:
17 June 2015
Abstract: Objectives: To detect average dimensions and indices of normal brain cerebral hemispheres and fourth ventricles in relation to age and gender. Subjects & Methods: 135 subjects; 70 males (M) and 65 females (F) were categorized into 4 age groups (G): GM1 & GF1 included subjects <20 years old, GM2 & GF2 included subjects aged 20-40 years, GM3 & GF3 included subjects aged 40-60 years and GM4 & GF4 included subjects >60 years old. CT imaging was conducted according to Agapejev; using high resolution scanner for measuring the fourth ventricle; the fourth ventricular anteroposterior diameter (AP), laterolateral diameter and fourth ventricular indices. Results: As regard the measured parameter of the fourth ventricle, the anteroposterior diameter (AP) and the laterolateral diameter (LL) showed a significant increase after the age of forty in both sexes. The indices of the fourth ventricle (AP/CR) and (AP/ff) showed no significant changes with age and sex but these indices had some degree of changes during human life time. On the other hand the only index that does not suffer influence of age and sex at all, it was (AP/LL) index. Considering the sex difference in ventricular dilatation in the present work, AP/LL was the only parameters which showed no difference between males and females so considered as (sentinel index of the fourth ventricle). Conclusion: The dimensions of the normal brain ventricles increased gradually and steadily between the age of one and fifty years, however they increased markedly and significantly thereafter in both sexes. This may be due to a physiological brain atrophy that may be encountered in most elderly individuals. Ventricular system was larger in males than that of females of all age groups.
Abstract: Objectives: To detect average dimensions and indices of normal brain cerebral hemispheres and fourth ventricles in relation to age and gender. Subjects & Methods: 135 subjects; 70 males (M) and 65 females (F) were categorized into 4 age groups (G): GM1 & GF1 included subjects <20 years old, GM2 & GF2 included subjects aged 20-40 years, GM3 & GF3 included subjects aged 40-60 years and GM4 & GF4 included subjects >60 years old. CT imaging was conducted according to Agapejev; using high ...
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Morphometric Study of the Normal Egyptian Coccyx from (Age 1-40 Year)
Saadia Ahmed Shalaby,
Essam Mohammed Eid,
Omar ABd Alaziz Allam,
Ali Mohammed Ali,
Mohammad Abdullah Gebba
Issue:
Volume 1, Issue 2, July 2015
Pages:
32-41
Received:
14 July 2015
Accepted:
24 July 2015
Published:
28 July 2015
Abstract: Background: Coccyx is named as resemblance to curved beak of the cuckoo. The coccyx is a triangular bone consisting of three to five segments: the first is the largest, it articulates with the sacrum. The last three segments are smaller and form a single bony piece. The anterior surface presents three transverse grooves indicating site of fusion of these segments. Aim of the Work: To study the normal variations of coccyx in number of segments, shape, size, curves, in different age groups by plain X-ray, MRI scan. Patients and Methods: Study was carried out on 200 normal Egyptian individuals, and were divided into 4 groups:- First group from the age of 1 up to ˂ 6 years. Second group from the age of 6 years up to ˂ 12 years. Third group from the age of 12 years up to ˂ 20 years. Fourth group from 20 years up to 40 years. Each one of these groups comprises 50 persons (25 males & 25 females). A full medical history was taken and each individual was subjected for plain X-ray on the pelvis (Anteroposterior & Lateral View) to study the variations of the coccyx, forty individuals were subjected to MRI scan as ten from each group. Results: Three coccygeal segments were present in 138 (68.3%) of individuals. Most of the subjects had coccyx type I (82; 41.0%) Fig.(2) , II (63; 31.5%), Fig.(3) III (25;12.5%) Fig.(4)IV(19; 9.5%) Fig.(5) and V(11; 5.5%), Fig.(6) Type I being more common among males. Joint subluxation was significantly more present among females. The sacrococcygeal structures were longer in men than women. However the coccyx was more ventrally angulated among females. Conclusion: Most of the Egyptian adults have a gently curved forward, or straight, coccyx composed of 3 segments. Sacrococcygeal morphologic findings that are associated with coccydynia, such as joint subluxation, spicule, and lateral deviation of coccygeal tip, commonly present in adult persons
Abstract: Background: Coccyx is named as resemblance to curved beak of the cuckoo. The coccyx is a triangular bone consisting of three to five segments: the first is the largest, it articulates with the sacrum. The last three segments are smaller and form a single bony piece. The anterior surface presents three transverse grooves indicating site of fusion of...
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Study of the Age Related Changes in the Lumbar Spine in Egyptian People Detected by Magnetic Resonance Imaging (MRI)
Gamal Abdel Salam,
Ahmed M. S. Hegazy,
Mohammed M. Mosaed,
Osama F. Ahmed,
Amgad N. Elsawy
Issue:
Volume 1, Issue 2, July 2015
Pages:
42-51
Received:
6 July 2015
Accepted:
24 July 2015
Published:
28 July 2015
Abstract: Lumbar region is the mobile part of the vertebral column which is a weight bearing region. Unfortunately, the available data detecting the lumbar spine degenerative changes by MRI are still limited, particularly in Egypt. The present study aimed to the examination of possible age related changes in the lumbar spine in Egyptian people detected by MRI. Mid sagittal MRI scan were obtained from eighty symptomless persons (30 females 37.5 % and 50 males 62.5% of cases) between 25- 70 years of age. They were divided into two groups ; first group forty cases, 25-40 years (21 males & 19 females) and the second group forty cases , 41-70 years (29 males & 11 females). From all samples, there were 38 normal (47.5%) and the abnormal cases were 42 (52.5 %). It was found collectively that the abnormalities were more in males than females and that was supplemented by x²- test (4.83) and p value (0.028). The following diseases were seen ; Subchondral sclerosis, osteophytes, disc degeneration , subchondral multiple small cysts, disc prolapse and spondolysis with variations in ages and sexes. In conclusuion it was found that, the lumbar region affected early by the age and more affected in males than in females
Abstract: Lumbar region is the mobile part of the vertebral column which is a weight bearing region. Unfortunately, the available data detecting the lumbar spine degenerative changes by MRI are still limited, particularly in Egypt. The present study aimed to the examination of possible age related changes in the lumbar spine in Egyptian people detected by MR...
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