Inflammatory Bowel Disease: Anatomical and Histopathological Study
Ahmed M. S. Hegazy,
Mohammed M. Mosaed,
Taha M. M. Hassan
Issue:
Volume 1, Issue 1, May 2015
Pages:
1-7
Received:
28 April 2015
Accepted:
4 May 2015
Published:
7 May 2015
Abstract: Worldwide, the frequency of chronic inflammatory bowel disease (CIBD), including ulcerative colitis (UC) and Crohn's disease (CD) increased rapidly through the last century making their histopathological diagnosis daily task for all pathologists. The accurate histopathological diagnosis of UC and CD requires an intimate correlations between the clinical, laboratory and endoscopic findings in conjunction to the suitable obtained biopsy material, as there are several diagnostic confusions between CIBD and non CIBD forms. The aim of this study was to focus and analyze certain practically selected histopathological features for the diagnosis of UC and CD including crypt architectural abnormalities, inflammation and an associated dysplasia or adenocarcinoma. This present study was performed on 100 specimens of tissue samples taken from small and large bowel including 3 ileocecal resections which were done for suspected an IBD. All the tissue samples received fixed in 10% neutral buffered formalin fixative solution, and paraffin-embedded tissue sections were prepared and examined microscopically for the histopathological features which distinguishing CIBD from non CIBD colitis. This study revealed 95 cases CIBD, among them 55 cases CD and 40 cases were UC, whereas the remaining 5 cases were non CIBD colitis. This study concluded that the diagnosis of IBD needs interdepartmental correlations to avoid under- or over-diagnosis. As well as the accurate discrimination of CIBD from non CIBD forms, differentiate UC from CD, and to identify any dysplastic lesions which is the backbone for therapeutic and prognostic strategies.
Abstract: Worldwide, the frequency of chronic inflammatory bowel disease (CIBD), including ulcerative colitis (UC) and Crohn's disease (CD) increased rapidly through the last century making their histopathological diagnosis daily task for all pathologists. The accurate histopathological diagnosis of UC and CD requires an intimate correlations between the cli...
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Treatment of Gingival Hyperpigmentation Using CO2 Laser: A Case Report
Ahmed M. S. Hegazy,
Bakr Ahmed Bakr,
Ehab Kamal Ali Hassan
Issue:
Volume 1, Issue 1, May 2015
Pages:
8-12
Received:
13 May 2015
Accepted:
17 May 2015
Published:
22 May 2015
Abstract: The gingival complex plays a vital role in the overall esthetics of a smile. Melanin, a brown pigment, is the most common natural pigment contributing to endogenous pigmentation of the gingiva. For depigmentation of gingiva different treatment modalities have been reported like bur abrasion, scraping, partial thickness flap, cryotherapy, electrosurgery and laser but repigmentation of the melanin pigment after surgical procedure is noted and considered in a high percentage. The present article describes and discusses one case of gingival melanin pigmentation, a 23-year-old female, who is medically fit and free of any systemic condition, complaining of dark pigmented gingivae. The CO2 laser device (OpusDuo Aqualite EC Lumens group of companies Germany) was used for treatment delivered in the present case. The clinical view 6 months after the treatment shows healthy gingival color. Conclusion: Treatment of hyperpigmentation by CO2 laser radiation in a defocused mode was found to be a safe, effective procedure and easy to perform. Postoperative patient satisfaction in term of esthetics and pain was excellent. The gingivae healed uneventfully and completely regenerated with no infection or scarring. No repigmentation occurred after 6 months period. Based on these observations, CO2 laser is a good treatment choice for gingival depigmentation.
Abstract: The gingival complex plays a vital role in the overall esthetics of a smile. Melanin, a brown pigment, is the most common natural pigment contributing to endogenous pigmentation of the gingiva. For depigmentation of gingiva different treatment modalities have been reported like bur abrasion, scraping, partial thickness flap, cryotherapy, electrosur...
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